Enzymatic electrochemiluminescence sensor based on a ternary luminol–H ₂ O ₂ -confined nanocatalyst system for sensitive determination of uric acid

, which is subsequently decomposed by the PtNPs-NGQDs nanocomposite, leading to enhanced ECL emission. Under optimized conditions, the sensor exhibits two linear response ranges for UA (0.01-1 µM and 1-50 µM) and a low detection limit of 8.1 nM (S/N = 3). The sensor also demonstrates good selectivity and stability, enabling reliable UA quantification in complex urine samples. This work provides a simple and versatile strategy for constructing sensitive ECL enzymatic platforms suitable for the detection of metabolites.