Siqi He, Jilu Lang, Chuang Mei, Yuanxiang Wen, Zhifeng Xu
Totally implantable venous access ports (TIVAPs) are widely used to provide reliable vascular access for chemotherapy in patients with malignancies. However, they may rarely give rise to catheter-related right atrial thrombus (CRAT), a potentially life-threatening complication. Here, we report a case of a patient with breast cancer who developed a right atrial thrombus following chemotherapy administered through a TIVAP. As anticoagulation therapy failed to resolve the thrombus, the patient subsequently underwent totally thoracoscopic beating-heart thrombectomy. Multimodality imaging played a pivotal role in localizing the intracardiac mass and characterizing its features, thereby guiding surgical planning. This case demonstrates that totally thoracoscopic beating-heart surgery is a safe and feasible treatment option for CRAT, offering favorable clinical outcomes and excellent cosmetic results, with promising potential for broader clinical application.