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◆ Peer Review2026-07-31· Gingival recession

Ozonized advanced platelet-rich fibrin for root coverage procedures: an 15-month case report

Mateus Pacer de Lima, Giovanna Sayumi de Sousa Sato, Alana Zenilda Thomaz Sacht, Isabela ramos Lesniewski, Vitoria Bortolon Jassniker, Maria Ritha Veiga Colognese, Carlos Augusto Nassar, Patrícia Oehlmeyer Nassar

原始摘要(英文原文)· Original abstract
Background: To demonstrate the feasibility and clinical outcomes of ozonated advanced platelet-rich fibrin (A-PRF) for root coverage of Cairo type 1 gingival recessions. Methods: A patient presenting with two Cairo type 1 gingival recessions was treated using ozonated A-PRF associated with the tunneling technique. Clinical evaluations at baseline and after 15 months assessed probing depth, clinical attachment level, recession height, and width of keratinized tissue. Results: The root coverage procedure resulted in partial root coverage, with an increase in keratinized gingiva and improvement in clinical attachment level. Conclusion: In this clinical case, ozonated A-PRF proved to be a viable alternative for the treatment of Cairo type 1 gingival recessions. The association with ozone represents a promising hypothesis for enhancing the biological performance of A-PRF and may potentially become an alternative to currently available biomaterials. However, further studies with larger sample sizes are needed to confirm this possibility.
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