Anna Tsiakiri, Spyridon Plakias, Georgios Giarmatzis, Georgia Tsakni, Foteini Christidi, Georgia Karakitsiou, Vasiliki Georgousopoulou, Georgios Manomenidis, Dimitrios Tsiptsios, Κonstantinos Vadikolias, Nikolaos Aggelousis, Pinelopi Vlotinou
The progressive nature of dementia necessitates early detection strategies capable of identifying preclinical cognitive decline. Gait disturbances, mediated by higher-order cognitive functions, have emerged as potential digital biomarkers in this context. This bibliometric review systematically maps the scientific output from 2010 to 2025 on the application of wearable sensor technologies and gait analysis in the early diagnosis of dementia. A targeted search of the Scopus database yielded 126 peer-reviewed studies, which were analyzed using VOSviewer for performance metrics, co-authorship networks, bibliographic coupling, co-citation, and keyword co-occurrence. The findings delineate a multidisciplinary research landscape, with major contributions spanning neurology, geriatrics, biomedical engineering, and computational sciences. Four principal thematic clusters were identified: (1) Cognitive and Clinical Aspects of Dementia, (2) Physical Activity and Mobility in Older Adults, (3) Technological and Analytical Approaches to Gait and Frailty and (4) Aging, Cognitive Decline, and Emerging Technologies. Despite the proliferation of research, significant gaps persist in longitudinal validation, methodological standardization, and integration into clinical workflows. This review emphasizes the potential of sensor-derived gait metrics to augment early diagnostic protocols and advocates for interdisciplinary collaboration to advance scalable, non-invasive diagnostic solutions for neurodegenerative diseases.