Helen G. Liley, Gary M. Weiner, Myra H. Wyckoff, Yacov Rabi, Georg M. Schmölzer, Maria Fernanda Branco de Almeida, Daniela T. Costa-Nobre, Peter G. Davis, Jennifer A. Dawson, Walid El‐Naggar, Jorge Fabres, Joe Fawke, Elizabeth E. Foglia, Ruth Guinsburg, Tetsuya Isayama, Mandira Daripa Kawakami, Henry Lee, R. John Madar, Christopher J. D. McKinlay, Victoria J. Monnelly, Firdose Nakwa, Mario Rüdiger, Anne Lee Solevåg, Takahiro Sugiura, Daniele Trevisanuto, Viraraghavan Vadakkencherry Ramaswamy, Nicole K. Yamada, Marlies Bruckner, Emer Finan, David Honeyman, Daniela Ríos, Justin Josephsen, C. Omar F. Kamlin, Vishal Kapadia, Anup Katheria, Bin Huey Quek, Shalini Ramachandran, Charles Christoph Roehr, Anna Lene Seidler, Marya L. Strand, E Udaeta-Mora, Katherine M. Berg
The International Liaison Committee on Resuscitation continually reviews new, peer-reviewed cardiopulmonary resuscitation science and publishes comprehensive reviews every 5 years. The Neonatal Life Support chapter of the 2025 International Liaison Committee on Resuscitation Consensus on Science With Treatment Recommendations addresses all published resuscitation evidence reviewed by the Neonatal Life Support Task Force science experts since 2020. This summary addresses 40 questions on population, intervention, comparator, and outcomes, addressing all parts of the Neonatal Resuscitation Algorithm. The summary includes 4 new systematic reviews, 2 new scoping reviews, and evidence updates for other topics. Members of the Neonatal Life Support Task Force have assessed, discussed, and debated the quality of the evidence on the basis of Grading of Recommendations Assessment, Development, and Evaluation criteria, and their statements include consensus treatment recommendations. Insights into the deliberations of the task force are provided in the Justification and Evidence-to-Decision Framework Highlights sections. In addition, the task force lists priority knowledge gaps for further research. Key Words: AHA Scientific Statements • cardiopulmonary resuscitation • ILCOR • infant • neonatal resuscitation.