Francesco De Maria, Paolo Fusco, Alessandro Russo
Dating applications have become central components of contemporary sexual networks, yet HIV prevention remains largely organised outside these digital environments. We propose that dating applications should be conceptualised as potential HIV and sexual health prevention ecosystems, connecting testing, PrEP and PEP navigation, STI services, vaccination, telemedicine, partner notification, behavioural support, and artificial intelligence-enabled health navigation. Existing evidence supports the effectiveness of many of these digital interventions individually, while emerging integrated models suggest opportunities to connect digital engagement with real-world care pathways. Artificial intelligence may provide an additional navigation layer capable of improving personalisation and continuity across prevention services. However, implementation will require careful attention to privacy, governance, equity, healthcare accessibility, and differences across health systems. Rather than replacing existing healthcare services, digital prevention ecosystems could complement them by bringing prevention closer to the environments where sexual interactions increasingly originate.