Braxton A. Linder, Soolim Jeong, Nina L. Stute, Omar B. El‐Kurd, Joseph D. Vondrasek, Andrew Pasternak, James R. Bagley, Joseph C. Watso, Zachary J. Schlader, Matthew C. Babcock, Gregory J. Grosicki, Austin T. Robinson
Urinary concentrations of several acute kidney injury (AKI) biomarkers increased after completing the 2023 Western States Endurance Run; however, there were no changes in renal blood flow in a subset of runners. When normalized to creatinine, several AKI biomarkers, including IGFBP7·TIMP2 (an FDA-approved biomarker of AKI), remained elevated. Notably, finishing the race euhydrated appeared to have a protective effect, mitigating increases in IGFBP7·TIMP2.