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◆ American Journal of Physiology-Regulatory, Integrative and Comparative Physiology2026-06-10· Medicine

Water intake mediates cross-sectional associations between urinary kidney injury biomarkers and race in emerging adults

Jake P. Muma, Braxton A. Linder, Nina L. Stute, Sofia O. Sanchez, Christin Domeier, Joseph C. Watso, Matthew C. Babcock, Roger S. Zoh, Orlando M. Gutiérrez, Zachary J. Schlader, Thomas E. Fuller‐Rowell, Austin T. Robinson

原始摘要(英文原文)· Original abstract
Apparently healthy emerging Black adults exhibited higher concentrations of several kidney injury biomarkers, collected via a 24-h urine sample, compared with White adults. Racial group differences in all kidney injury biomarkers tested, except for TIMP-2 × IGFBP7 (the only FDA-approved urinary kidney injury biomarker), were attenuated once indexed to urinary hydration markers. Water intake mediated the racial group difference in TIMP-2 × IGFBP7. Future work is needed to determine whether hydration interventions could mitigate racial differences in TIMP-2 × IGFBP7.
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Water intake mediates cross-sectional associations between urinary kidney injury biomarkers and race in emerging adults — 科研速览 Science Skim