Reexamining the evolutionary history of the mammalian medial pterygoid muscle

ABSTRACT In non-mammalian synapsids, feeding and hearing are closely linked because some jaw bones are involved in both functions. The evolutionary decoupling of these two systems in early mammals likely catalyzed greater specialization of feeding and hearing. Although fossil osteological changes during this process are well documented, the corresponding evolutionary changes to soft tissue anatomy are less certain. The medial pterygoid muscle is a jaw adductor that is central to this evolutionary transition because in many fossil lineages it inserted near or possibly on jaw bones involved in both feeding and hearing. In therians (placentals and marsupials), the medial pterygoid muscle develops medial to Meckel’s cartilage and inserts on the mandibular angular process. Similarly, non-mammalian cynodonts are often reconstructed with a medial pterygoid muscle passing medial to the ossified Meckel’s cartilage, inserting on the dentary ‘angular’ (i.e., pseudangular) process. Thus, the traditional interpretation is that the medial pterygoid remained medial to Meckel’s cartilage through the evolutionary transitions from early cynodonts to therians. Here we highlight issues with that interpretation: the medial pterygoid muscle inserts lateral (not medial) to Meckel’s cartilage in monotremes and, presumably, early mammal groups (e.g., spalacotherioids) that lacked an angular process. This suggests at least two possible explanatory hypotheses: 1) the medial pterygoid muscle is evolutionarily labile, shifting in position relative to Meckel’s cartilage multiple times or 2) the medial pterygoid muscle did not insert on the pseudangular process of non-mammalian cynodonts and instead inserted on the mandibular medial ridge, dorsal to Meckel’s cartilage. We advocate for the latter hypothesis, proposed by Patterson (1956), which suggests that the medial pterygoid did not shift medial to Meckel’s cartilage until the complete separation of the ear and jaw in cladotherians (therians and close relatives), with the shift in position possibly triggering the evolution of the therian angular process as an insertion site. Patterson’s hypothesis is in line with a growing body of evidence that indicate concomitant evolutionary changes of muscles, ears, and jaws at the cladotherian node were important catalysts for the evolution of hearing and feeding specializations in extant mammals.