Unveiling molecular dynamics: the effects of functional mandibular advancement and a one-month recovery period on myostatin and myosin-1c gene expression in masticatory muscles of young male Wistar rats.

Functional mandibular advancement appliances are widely used in orthodontics, but their molecular and histological effects on masticatory muscles remain underexplored. This study evaluated gene expression and tissue-level adaptations in response to mandibular advancement and a subsequent recovery period in young male Wistar rats.