Forces and Moments Generated by Thermoforming Aligners and Direct-Printed Aligners: A Systematic Review.

Objectives: This systematic review aims to compare the forces and moments generated by thermoforming aligners and direct-printed aligners in guiding tooth movement in orthodontic patients, evaluating their impact on orthodontic outcomes. Methods: A systematic search was conducted in PubMed, Web of Science, and Scopus databases, covering studies on thermoforming and direct-printed aligners from inception to October 2024. Eligible studies included randomized controlled trials, quasi-experimental studies, and observational studies assessing forces and moments generated by these aligners on teeth. In vitro studies pertinent to the topic were also considered. Data extraction focused on study characteristics, aligner details, force and moment measurements, and clinical outcomes. Quality assessment utilized the ROBINS- I for Risk of Bias. The review has been registered on PROSPERO CRD42024620341. Results: A total of nine studies met the inclusion criteria. Findings indicate that thermoforming aligners, while effective in initial force application, exhibit significant force decay over time due to material stress relaxation. In contrast, direct-printed aligners maintain more consistent force levels, potentially resulting in more predictable and sustained tooth movement. Both aligner types vary in their ability to control force direction and magnitude, with direct-printed aligners showing advantages in customization and force retention. Conclusions: The biomechanical properties of thermoforming and direct-printed aligners offer distinct advantages and limitations. Direct-printed aligners may enhance clinical predictability and reduce treatment time through consistent force application, though further research is necessary to validate these benefits in clinical settings. This review underscores the importance of material selection and fabrication method in optimizing orthodontic outcomes.