Zhengqi Li, Yuntao Nie, Pengpeng Wang, Baoyin Liu, Biao Zhou, Nianrong Zhang, Siqi Wang, Sai Chou, Zhe Wang, Hua Meng
Objectives The incidence of regaining weight after laparoscopic sleeve gastrectomy (LSG) is high. TONGEE duodenum-jejunal bypass liner (DJBL) has been proven to reduce the weight of obese patients. The present study aims to investigate the effect of TONGEE DJBL on weight loss in patients who have regained weight after LSG. Methods A cohort study with two nonrandomized groups was conducted at the China-Japan Friendship Hospital in Beijing. The recruitment period was from August 2023 to September 2025 for patients with simple obesity undergoing DJBL treatment and those who had regained weight after LSG surgery. We then compared the weight loss effects of the two groups using univariate and multivariate analyses. Results A total of 30 patients with simple obesity and 16 patients who had regained weight after LSG surgery were recruited. The incidence of complications in the two groups, total weight loss percentage (10.98 ± 5.96 vs10.36± 3.78, 95% CI: 8.84, 13.11), and excess weight loss percentage (50.87 ± 37.28 vs 50.38 ± 29.16, 95% CI: 37.54, 64.22) do not have statistical difference ( P > 0.05). Three months after TONGEE DJBL surgery, both groups of patients showed a decrease in body fat percentage and an increase in muscle percentage. Conclusions TONGEE DJBL can be used as an endoscopic treatment option for patients who regain weight after LSG surgery.