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◆ The Analyst2026-08-10

An aggregation-induced electrochemiluminescence sensor for ochratoxin A detection integrating CRISPR-Cas12a and tetrahedral DNA nanostructures.

Zhi-Hong Xu, Xin Weng, Meng-Ping Zhang, Ruo-Mei Lin, Wen Xu, Han Wu, Hang Gao

原始摘要(英文原文)· Original abstract
An aggregation-induced electrochemiluminescence (AIECL) biosensor combining CRISPR-Cas12a and tetrahedral DNA nanostructures (TDNs) is fabricated for OTA detection, with polymer dots (Pdots) serving as emitters. The sensor achieves favorable analytical performance, with a limit of detection of 0.41 pg mL-1, showing promising applications in food security monitoring.
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An aggregation-induced electrochemiluminescence sensor for ochratoxin A detection integrating CRISPR-Cas12a and tetrahedral DNA nanostructures. — 科研速览 Science Skim