Pan Zhu, Yu Tang, Yuanyu Tang, Shaojing Zhao, Fei Long, Chaoyi Yao, Benhua Wang, Xiangzhi Song, Yi Zhang, Chaochao Tan, Minhuan Lan
and was successfully employed in imaging of NTRase in 4T1 tumor-bearing mice. The findings demonstrate the potential of the NTR-TCN-CL probe in real-time assessment of tumor-associated NTRase activity in the tumor microenvironment and highlight its utilizability as a noninvasive tool for monitoring of the hypoxia-related biomarker.