Post-prescription review of antibiotics for pediatric urinary tract infection is an effective ambulatory antibiotic stewardship strategy.

Pharmacist-led review of antibiotic courses post-prescription for possible urinary tract infections (UTI) in ambulatory pediatric patients was associated with increased antibiotic changes for antibiotic resistant infections, increased antibiotic discontinuations for negative cultures, and decreased 30-day UTI admissions. Notable process changes included standardizing susceptibility interpretation and creating an antibiotic discontinuation process.