Current Applications of Molecular Imaging in Adrenal Imaging.

This clinical review explores adrenal incidentalomas, masses, and pathologies through a comprehensive evaluation of molecular imaging modalities. Molecular imaging is important in the diagnostic and therapeutic management of adrenal gland lesions and masses. Targeted radiopharmaceutical therapies, 131I-MIBG and 177Lu-DOTATATE (Lutathera), and newer theranostic agents can provide personalized treatment plans for patients. This review discusses molecular imaging based on adrenal tumor biology, receptor expression, and genetic mutations, the imaging characteristics of common adrenal lesions, and current and future therapeutic treatments.