Tzu-Fei Wang, Grégoire Le Gal, Marc Carrier
Subsegmental pulmonary embolism (SSPE) accounts for 5-10% of PE diagnoses, but the optimal diagnostic and management strategies, as well as the long-term outcomes remain debatable. Recent studies have provided more insights into outcomes in this population, and a randomized controlled trial is ongoing to evaluate the role of anticoagulation in patients with isolated SSPE. In this article, we use cases to illustrate the challenges in diagnosis and to discuss management approaches. We aim to provide evidence-based recommendations whenever possible and point out potential areas for future research.