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◆ Clinical Oral Investigations2026-06-04· Ridge

Simultaneous implant placement with guided bone regeneration for horizontal ridge augmentation using a 3D-preformed resorbable PLGA membrane: A prospective single-arm clinical study

Sang‐Hyun Son, Kyeong-Ok Lim, Seo-Hee Han, Gwi-Hyeon Min, Jooseong Kim, Tadeusz Morawiec, Won‐Pyo Lee

原始摘要(英文原文)· Original abstract
OBJECTIVES: This study aimed to evaluate the clinical effectiveness and safety of guided bone regeneration (GBR) using a three-dimensional preformed resorbable Polylactic-co-glycolic acid membrane (3D-PRPM) with simultaneous implant placement. MATERIALS AND METHODS: Twenty patients (21 sites) with localized ridge defects were treated using implants placed concurrently with GBR using a 3D-PRPM. Cone-beam computed tomography scans were taken preoperatively, immediately postoperatively, and at 5 months. Horizontal bone augmentation (BA), hard tissue gain (HG), bone resorption (BR), and hard tissue gain rate (HGR) were assessed. Changes beyond the original bony envelope were evaluated. Statistical analyses included the Wilcoxon signed-rank and Friedman tests. RESULTS: Mean BA was 2.99 ± 1.15 mm, and mean HG at 5 months was 2.64 ± 1.10 mm. Mean BR was 0.35 ± 0.23 mm, and mean HGR was 87.2% ± 8.2%. Envelope analysis confirmed a significant increase after augmentation with partial reduction during healing; however, ridge dimensions at 5 months remained significantly greater than baseline (P < 0.001). No membrane exposure, infection, or wound dehiscence occurred. CONCLUSION: 3D-PRPM enabled predictable horizontal ridge augmentation with excellent volumetric stability and favorable short-term safety. CLINICAL RELEVANCE: A 3D-PRPM may provide a stable, fixation-free resorbable barrier for horizontal ridge augmentation, potentially simplifying GBR procedures and reducing the need for secondary removal.
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Simultaneous implant placement with guided bone regeneration for horizontal ridge augmentation using a 3D-preformed resorbable PLGA membrane: A prospective single-arm clinical study — 科研速览 Science Skim