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◆ ChemistrySelect2026-03-01· Chemistry

Cobalt‐Catalyzed Aerobic Oxidation of Arylmethylamines to Arylamide

Shiyun Li, Jie Hu, Linlin Wang, Yan An, Jun Huang, Huaiyin Chen, Yuanqing Dong

原始摘要(英文原文)· Original abstract
ABSTRACT A cobalt‐catalyzed aerobic oxidation of (aryl)methanamines for the synthesis of aryl amides has been developed. DMAP was identified as an efficient ligand, and molecular oxygen serves as a sustainable and environmentally benign oxidant. The protocol delivers high yields, excellent chemoselectivity, broad substrate scope, and operational simplicity. The reaction mechanism has been thoroughly investigated, and the demonstrated practicality and efficiency render this method highly promising for widespread applications in organic synthesis.
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Cobalt‐Catalyzed Aerobic Oxidation of Arylmethylamines to Arylamide — 科研速览 Science Skim