Takeru Kajiyama, Kohei Kanazaki, V. Gopinath, Puteri Shafinaz Abdul‐Rahman, Ayami Matsushima
Bisphenol A (BPA) is a widely used industrial chemical used in the production of polycarbonate and epoxy resins; however, it is also recognized as an endocrine-disrupting chemical. This review examines scientific evidence on the migration of bisphenol A and its derivatives from epoxy can coatings into food products, highlighting the factors that have prompted recent regulatory shifts. The newly enacted Commission Regulation (EU) 2024/3190 addresses health concerns by promoting the use of BPA-Non-Intent (BPA-NI) materials, which are formulated to avoid intentional BPA use and minimize contamination. This regulation is expected to significantly reduce the leaching of bisphenol A and its derivatives from epoxy resins into food and beverage cans, thereby enhancing consumer safety. This review also discusses key challenges and future directions for developing and evaluating BPA-NI products and underscores the importance of continued research and innovation in this field.