The potential risk of type 2 diabetes mellitus and coagulopathies associated with consumption of energy drinks.

INTRODUCTION: The consumption of energy drinks (EDs) has risen in recent years and is associated with numerous health concerns. This study aims to evaluate the effects of EDs consumption on blood glucose, HbA1c, hematological, coagulation parameters, and liver markers in mice. MATERIALS AND METHODS: Twenty mice were equally divided into two groups; one group served as a control and the other was given EDs. After four months, blood glucose, HbA1c, hematological, coagulation profile, and liver markers were analyzed using an unpaired t-test. RESULTS: Results showed that mice fed EDs had higher blood glucose and HbA1c. In addition, platelet count was lower, whereas levels of prothrombin time, activated partial thromboplastin time, international normalized ratio and D-dimer were higher in ED-treated group, with reduced levels of fibrinogen. Results showed that levels of alanine aminotransferase, aspartate aminotransferase, alkaline phosphatase were significantly higher in ED-treated mice, while total protein and albumin were reduced. CONCLUSION: These data suggest that the intake of EDs potentially increases the risk of type 2 diabetes mellitus and coagulation abnormalities.