Kevin Wamae
This replication package contains all data, scripts, and outputs used in the study "A scoping review of antimalarial drug resistance markers in Kenya (1987–2022): toward a National Surveillance Framework and Data Repository."
The repository provides a reproducible workflow for the identification, extraction, standardization, analysis, and visualization of published molecular surveillance data on Plasmodium falciparum antimalarial drug resistance in Kenya.
The package includes:
01-scripts R scripts used for data cleaning, harmonization, analysis, mapping, and figure generation. 02-search terms Search strategies used across bibliographic databases. 03-studies Bibliographic records and retrieved studies from PubMed, Embase, Scopus, Web of Science, and Google Scholar. 04-extracted-data Curated datasets containing allele frequencies, microhaplotype frequencies, and mapping information extracted from eligible studies. 05-output Reproducible analytical outputs, including tables, figures, maps, and summary datasets presented in the publication. 06-mapping Geographic reference files and shapefiles used to generate spatial visualizations. The repository aggregates data from 110 published studies and serves as a reproducible resource for malaria molecular surveillance, resistance monitoring, and future development of a national antimalarial drug resistance data repository for Kenya.
Directory structure:
01-scripts
02-search terms
03-studies embase
google-scholar
pubmed
scopus
web-of-science
04-extracted-data genotypes-alleles
genotypes-microhaplotypes crt
dhfr
dhfr-dhps
dhps
mdr1
mapping
05-output alleles
datapoints
graphs
maps
microhaplotypes
tables alleles
datapoints
haplotypes
06-mapping 01-shapefiles ken_adm_iebc_20191031_shp
ken_lakes
kenya-sublocations