Apocrine Hidrocystoma of the Lower Eyelid: A Case Report.

Apocrine hidrocystoma is an uncommon benign cystic neoplasm of apocrine gland origin that most frequently occurs in the head and neck region, particularly around the eyelids. Because its clinical appearance is often nonspecific, it may be difficult to distinguish from other benign eyelid cystic lesions before excision. We report the case of a 33-year-old man who presented with a painless, skin-colored subcutaneous mass on the medial aspect of the left lower eyelid. The patient reported no seasonal change in lesion size, and no conjunctival abnormality was observed. The lesion was clinically suspected to be a benign cystic tumor and was excised under local anesthesia. Histopathological examination revealed a cyst lined by one to two layers of cuboidal to columnar epithelial cells with papillary infoldings and characteristic apical decapitation secretion. An outer myoepithelial cell layer was also identified. There was no cytological atypia or mitotic activity, and the lesion was diagnosed as an apocrine hidrocystoma. The postoperative course was uneventful, with no evidence of recurrence at the one-month follow-up. This case illustrates the clinicopathological features of apocrine hidrocystoma and emphasizes the role of histopathological examination in the definitive diagnosis of clinically nonspecific eyelid cystic lesions.