Reconstruction of a Giant Gluteal Neurofibroma Using an Advancement Flap and Gluteal Lift in Neurofibromatosis Type 1.

Neurofibromatosis type 1 (NF1) is an autosomal dominant disorder characterized by the development of multiple neurofibromas that may cause pain, functional impairment, and significant aesthetic deformity. Extensive gluteal lesions represent a reconstructive challenge because of poor tissue quality, wound tension, and the high risk of postoperative wound complications. We report the case of a 43-year-old man with NF1 who presented with a giant left gluteal cutaneous neurofibroma causing marked soft-tissue deformity. The lesion was completely excised, and the resulting defect was reconstructed using local advancement flaps combined with gluteal lifting. Although postoperative wound dehiscence occurred, it was successfully managed with conservative treatment, resulting in complete wound healing and satisfactory functional and aesthetic outcomes. This case highlights the importance of individualized reconstructive planning and demonstrates that combining local advancement flaps with gluteal lifting can provide effective soft-tissue coverage and contour restoration following resection of extensive gluteal neurofibromas, contributing to the limited literature on reconstruction of these uncommon defects.