Catelina C Nguyen, Jennifer S Chiang, Erqi Pollom, Elham Rahimy, Laurie Tupper, Melanie H Gephart, Michael Lim, Thomas J Wilson, Steven D Chang, Scott G Soltys
Malignant melanotic nerve sheath tumors (MMNSTs) are rare tumors with uncertain clinical behavior. Standard treatment includes surgical resection; however, the potential benefit of adjuvant radiotherapy remains unclear. We present four patients with MMNSTs who were treated with stereotactic radiosurgery following either partial or gross total resection. The series included two females and two males, ranging in age from 18 to 72 years, with tumors located in the spine or intracranially. At follow-up intervals of 1.6, 1.8, 3.5, and 6.0 years after radiosurgery, all tumors remained controlled, with radiographic stability and no evidence of metastatic disease.