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◇ PubMed2026-09-11· CRISPR

Intersecting experimental evolution and CRISPR screens to identify novel toxin resistance loci.

Michele Marconcini, Steeve Cruchet, Srishti Goswami, Raghuvir Viswanatha, Matthew Butnaru, Joydeep De, Camilla Roselli, Dafni Hadjieconomou, Norbert Perrimon, Stephanie E. Mohr, Richard Benton

原始摘要(英文原文)· Original abstract
reduced OA tolerance. Our identification of genes contributing to OA resistance in laboratory and natural contexts demonstrates how complementary selection approaches can provide insights into complex mechanisms of toxin susceptibility and adaptation. Such methods could have practical applications in the characterization of natural and artificial insecticides.
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Intersecting experimental evolution and CRISPR screens to identify novel toxin resistance loci. — 科研速览 Science Skim