Medico Legal aspects on Low-Grade Biofilm Infection to MDR Nosocomial Prosthetic Joint Infection.

Prosthetic joint infections (PJI) are among the most challenging complications of orthopedic surgery, particularly when involving both biofilm-forming low-virulence organisms and multidrug-resistant (MDR) pathogens. This report outlines the complex pathophysiology and clinical challenges associated with PJI, transitioning from a low-grade chronic infection to an acute MDR nosocomial infection, highlighting significant medicolegal implications.