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◆ Theranostics2025-12-06· Neurodegeneration

Chronic intermittent hypoxia increases Parkinson's disease susceptibility via PPARα-mediated lipid droplet-mitochondrial dysfunction

Mingrui Zhai, Jie Pan, Zhengwang Wu, Yu-Ying He, Kai Zhang, Long Ren, Yurong Wang, Yibing Li, Jun Gao, Lei Xiao, Yuehua Liu

原始摘要(英文原文)· Original abstract
This study reveals a previously unrecognized LD-mitochondrial regulatory axis underlying CIH-associated PD pathology and highlights its potential as a therapeutic target against CIH-accelerated neurodegeneration.
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Chronic intermittent hypoxia increases Parkinson's disease susceptibility via PPARα-mediated lipid droplet-mitochondrial dysfunction — 科研速览 Science Skim