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◆ Theranostics2025-11-20· Cancer research

Lactylation-driven <i>NSUN2</i> -mediated RNA m5C modification promotes perineural invasion in pancreatic cancer

Tianhao Huang, Chonghui Hu, Huimou Chen, Honghui Jiang, Tingting Li, Qing Tian, Rihua He, Yuan Yuan, Yong Jiang, Yu Zhou, Qing Lin, Zhihua Li, Mingming Xiao, Xuebiao Wei, Rufu Chen, Shangyou Zheng

原始摘要(英文原文)· Original abstract
axis that links metabolic stress-induced lysine lactylation to mRNA methylation-dependent stabilization of pro-invasive transcripts, highlighting actionable therapeutic targets to restrain neural invasion and improve patient outcomes.
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Lactylation-driven <i>NSUN2</i> -mediated RNA m5C modification promotes perineural invasion in pancreatic cancer — 科研速览 Science Skim