Accelerated cartilage regeneration via chondrocyte metabolic reprogramming using nano-steroid-conjugated mesenchymal stem cells in osteoarthritis
Jong Yeong Lee, Jun Young Park, In Ah Kwon, Su Hyun Lim, Ki Bum Kim, Junyoung Park, Youn Joo Kang, Sang Hyun Kim, Dongwoo Khang, Jin Kyeong Choi
原始摘要(英文原文)· Original abstract
MSC-Au-Steroid represents a promising multifactorial therapeutic candidate for OA by targeting both metabolic reprogramming and immune modulation. These findings provide strong evidence that MSC-Au-Steroid acts as a disease-modifying agent, addressing multiple pathological factors and offering superior efficacy compared to current therapies.