Channel-specific differential effects of bacterial mechanosensitive channels for ultrasound neuromodulation in precision sonogenetics
Xin Li, Chenguang Zheng, Yutao Tian, Dong Ming
原始摘要(英文原文)· Original abstract
This characterization provides insights for potential precision sonogenetics applications: MscS offers a biosafety-optimized option with minimal genomic footprint, whereas MscL-G22S enables modulation of neural oscillations. These findings contribute to the development of customized neuromodulation approaches for targeting pathological circuits in neurological disorders.