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◇ bioRxiv2026-09-18· bioinformatics

Rapid Shift Toward Pulsed Field Ablation and Precision Risk Stratification in High-Impact Atrial Fibrillation Research

Z. Su, T. Li

原始摘要(英文原文)· Original abstract
Conventional bibliometrics rely on lifetime citations, obscuring immediate shifts in cardiovascular research paradigms. To track emerging trends in atrial fibrillation management, we performed a comparative bibliometric analysis of the 50 highest-cited original research articles per year in OpenAlex topic T10065 across consecutive 2023 (Class of 2025) and 2024 (Class of 2026) publication cohorts. Articles were ranked using a fixed 18-month post-publication citation window, and extracted concepts were normalized into 719 canonical topics and 32 parent themes using large language model curation. Concept frequency tracking demonstrated a swift technological shift, with pulsed field ablation showing the largest topic frequency increase (+0.08, from 0.30 to 0.38) to become the leading canonical topic in 2024, displacing conventional thermal pulmonary vein isolation (-0.18, 0.40 to 0.22). Simultaneously, stroke prevention focus shifted toward refined predictive modeling, with increases in Risk Stratification and Predictive Models (+0.08, 0.30 to 0.38) and CHA2DS2-VASc scoring (+0.08, from 0.10 to 0.18). High-impact atrial fibrillation research is rapidly pivoting toward non-thermal ablation safety profiling and precision risk stratification, highlighting the utility of fixed-window concept mining for capturing real-time scientific evolution. Online explorer of the result is available at https://pri.pepkio.com.
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