Sailaja Choudary A, Sheethal H S, Kavitha Rao, Abhinethra M S, Manjula N, Manisha Rao, Meenal Kate
White spongy nevus (WSN) is an infrequent hereditary mucosal disorder that is asymptomatic and is marked by white corrugated plaques due to defects in epithelial keratinization. Therefore, it is of interest to report of a 20-year-old woman who has bilateral mucosal lesions of the buccal area that are non-responsive to antifungal treatment. WSN was established through clinical features and histopathology which include hyperparakeratosis, vacuolated spinous cells and perinuclear eosinophilic condensation. WSN is a benign disorder; however, it is often confused and should be distinguished with malignant and infectious lesions. Its clinical and genetic background is important for counselling and follow-up.