Aortic aneurysm and aorto-bi-iliac endoprosthesis infection caused by Helicobacter cinaedi diagnosed by next-generation sequencing: a case report.

Helicobacter cinaedi is an emerging Gram-negative pathogen, possibly involved in the pathogenesis of atherosclerosis and increasingly recognized as a cause of bacteraemia, cellulitis and vascular infections, particularly in immunocompromised and elderly patients. Infection of vascular grafts by H. cinaedi remains exceedingly rare. We report a case of H. cinaedi infection involving an aortic aneurysm and an aorto-bi-iliac endoprosthesis in an immunocompetent patient, highlighting the diagnostic challenges posed by culture-negative infections and the crucial role of Next-Generation Sequencing (NGS) in pathogen identification and therapeutic management.