Madhan Jeyaraman, Naveen Jeyaraman, Arulkumar Nallakumarasamy, Mainak Roy, Tomás Mosaner de Souza Moraes, Lucas Furtado da Fonseca
Musculoskeletal injuries are among the most common causes of disability worldwide, with early detection and appropriate intervention critical to minimizing long-term complications. Infrared thermography (IRT) has emerged as a non-invasive, real-time imaging modality that captures superficial temperature changes reflecting underlying physiological processes such as inflammation and vascular alterations. This review explores the fundamental principles of medical thermography, differentiates between passive and active approaches, and outlines key technological advancements including artificial intelligence integration. The clinical utility of IRT is discussed in various contexts - ranging from acute soft tissue injuries and overuse syndromes to chronic pain and rehabilitation monitoring. Comparative insights with conventional imaging techniques such as ultrasound and magnetic resonance imaging are also presented. While IRT offers functional imaging capabilities with advantages in portability, safety, and speed, its limitations - such as lack of deep-tissue penetration and protocol standardization - remain significant barriers to broader adoption. Future directions include the integration of IRT with other imaging modalities and digital health platforms to enhance musculoskeletal assessment and injury prevention strategies.