Ran Cui, Xing-Hua Luan, Sheng-Ming Dai
Sporadic late-onset nemaline myopathy (SLONM) is a rare muscle disorder that can be treated or may pose a potential threat to life. It usually manifests in the later stages of life and is characterized by the accumulation of nemaline rods within muscle fibers. The pathophysiology of this disease is still not fully understood, with some evidence suggesting that autoimmune responses and hematological neoplasia may be involved. Herein, a case of SLONM associated with systemic lupus erythematosus is presented, which showed a favorable response to immunotherapy. Cite this article as: Cui R, Luan X, Dai S. Nemaline myopathy in systemic lupus erythematosus. Eur J Rheumatol. 2026, 13(2), 0048, doi:10.5152/eurjrheum.2026.25045.