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◆ Journal of clinical research in pediatric endocrinology2026-04-03

Early-Onset Multiple Necrobiosis Lipoidica in a Child with Type 1 Diabetes Mellitus.

Emel Gül Açıkgöz, Özge Yanık, Şeyma Koca, Tuğba Kontbay Çetin, Gökhan Şahin

原始摘要(英文原文)· Original abstract
Necrobiosis lipoidica is uncommon in childhood, and a multifocal presentation early in the course of type 1 diabetes mellitus appears to be infrequently reported. In our patient, multiple lesions developed within 3 years of diabetes diagnosis, despite the absence of overt microvascular complications. The persistence of lesions alongside recurrent episodes of ketoacidosis may suggest a potential association between suboptimal metabolic control and cutaneous microangiopathic changes; however, causality cannot be established on the basis of a single case. Early recognition of such lesions may be clinically relevant, as they may prompt careful metabolic evaluation and closer follow-up in affected children.
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Early-Onset Multiple Necrobiosis Lipoidica in a Child with Type 1 Diabetes Mellitus. — 科研速览 Science Skim