Prognostic value of routine biomarkers in acute stanford type A aortic dissection: A retrospective cohort study

Aortic dissection is a serious clinical emergency in cardiovascular surgery and requires early diagnosis and rapid surgical intervention due to the high risk of death.The disease is characterized by the rupture of the intimal layer of the aortic wall, resulting in the passage of blood into the medial layer and the formation of a false lumen. [1]Currently, the most commonly used classification systems for aortic dissection are the DeBakey and Stanford classifications.Acute stanford type A aortic dissection (ATAAD), due to their involvement of the ascending aorta, exhibit a more aggressive clinical course and carry a high mortality risk. [2]Despite advances in surgical techniques, anesthesia management, and intensive care practices, reported mortality rates for ATAAD remain at approximately 18-25%, and the disease continues to be a lifethreatening clinical condition. [3] recent years, parallel to improvements in surgical outcomes, studies aimed at identifying high-risk patients in the preoperative period have gained importance.In particular, investigating the prognostic value of readily available and routinely assessable laboratory parameters is among the noteworthy issues in perioperative risk assessment. [4]ccumulating evidence suggests that inflammatory mechanisms contribute substantially to the development and progression of aortic dissection.Therefore, biomarkers reflecting the systemic inflammatory response are thought to be associated with mortality.