SM Ahsanul Kabir Ahsan, Sahil Mehta, Kamalesh Chakravarti, Sucharita Ray, Sandeep Grover, Rajveer Saharan, Vivek Lal
BACKGROUND: Non-motor symptoms have a more significant impact on the quality of life in Parkinson's disease than motor symptoms. OBJECTIVES: To evaluate the frequency of non-motor symptoms in Parkinson's disease and study their impact on quality of life. METHODS: A cross-sectional study was conducted on 100 patients with idiopathic Parkinson's disease. All patients underwent a detailed history and neurological examination, Hoehn and Yahr staging, MDS UPDRS scoring, NMSS scoring, and PDQ-39 scoring to assess their quality of life. RESULTS: All patients presented with at least one non-motor symptom. The most frequently affected non-motor symptom was sleep/fatigue (95%), followed by urinary (79%) and gastrointestinal dysfunction (76%). The total NMSS score significantly correlated with disease severity and quality of life. CONCLUSION: Non-motor symptoms are quite prevalent in patients with Parkinson's disease and significantly impact their quality of life.