Maria Infant Majula Shifani Mahendran, Vinoj Gopalakrishnan, Vaijayanthi Saravanan
Diabetic foot ulcers (DFUs) represent a major complication in patients with diabetes mellitus, resulting in reduced quality of life, frequent hospitalizations, and increased healthcare costs. Our study analyzed the clinical records of 200 patients with DFU selected from a pool of medical records from a tertiary care hospital in India. Our study assessed patterns of drug prescription, determined pathogen profiles and antimicrobial susceptibility, evaluated economic burden, and identified the prevalence and severity of drug-drug interactions (DDIs) among patients with DFUs. Antibiotics were the most commonly prescribed drugs (18.5%) with the highest incidence of serious DDIs (28.5%). These results underscore the importance of optimizing antibiotic stewardship and rational prescribing practices to improve clinical outcomes.