Punnya V Angadi, Karishma Desai, Vinay Hazarey, Praveen Arany, Raghu Radhakrishnan, Pratibha Ramani, Rajiv Desai, Jay G Ray, Alka Kale
Oral submucous fibrosis (OSMF) continues to be a challenging condition characterised by increasing stiffness of the mucosa, restricted mouth opening, and a risk of malignant transformation. In light of the persistent debates, the absence of a standardised treatment protocol, and the necessity for a cohesive understanding to guide clinical practice and research, a dedicated symposium was held on 5 November 2023 during the 30th National Conference of the Indian Association of Oral and Maxillofacial Pathologists. The aim was to evaluate the latest developments and establish a consensus on particular aspects of OSMF. Six experts, all from the specialty of Oral Pathology but with extensive and diverse research experience in various aspects of OSMF-including molecular mechanisms, histopathology, clinical correlations, emerging therapies, and public health perspectives-delivered presentations and answered focussed questions. The discussions were moderated by two accomplished academicians, who facilitated deliberations and guided the synthesis of consensus. Through thoughtful discussion, a consensus was reached regarding the pathogenesis, potential for malignancy, management strategies, exploration of photobiomodulation, EMT-based and regenerative therapies, and the strengthening public health measures. This report consolidates key deliberations and consensus recommendations from the symposium, aiming to provide a collaborative framework for future OSMF research and management.