Leonidas E Mastrokostas, Paul G Mastrokostas, Daniel Yusupov, Abigail Razi, Aaron B Lavi, Luke B Schwartz, Sean Inzerillo, Mohamed Said, Alexander Kucherina, Pemla Jagtiani, Arie Monas, John K Houten, Christopher K Kepler, Jad Bou Monsef, Afshin E Razi, Mitchell K Ng
Depression and psychotic disorders are common in PCDF and are linked to worse outcomes and higher resource use.
CONTEXT: Psychiatric comorbidity has been associated with worse perioperative outcomes and greater healthcare utilization after spine surgery.
AIMS: This study compared complications and healthcare utilization among posterior cervical decompression and fusion (PCDF) patients with depression, psychotic disorders, or no mental-health diagnosis.
SETTINGS AND DESIGN: Retrospective cohort analysis of the National Inpatient Sample from 2016 to 2022.
MATERIALS AND METHODS: The database was queried for elective adult PCDF encounters. Mental-health exposures were defined using Elixhauser indicators for depression and psychoses. Outcomes included medical complications, non-routine discharge, inpatient mortality, length of stay (LOS), and costs.
STATISTICAL ANALYSIS USED: Chi-square and multivariate logistic regression analyses were performed. Significance was set at the P < 0.05 level.
RESULTS: We identified 167,480 weighted admissions: 129,205 with no mental-health diagnosis, 32,500 with depression, and 5,775 with psychotic disorders. Depression was associated with higher odds of cardiovascular complications (odds ratio [OR]: 1.20, P < 0.001), mechanical complications (OR: 1.24, P < 0.001), a composite adverse-event outcome (OR: 1.17, P < 0.001), and nonroutine discharge (OR: 1.12, P < 0.001). Psychotic disorders were associated with higher odds of mechanical complications (OR: 1.44, P = 0.002), nonroutine discharge (OR: 1.32, P < 0.001), and inpatient mortality (OR: 2.33, P = 0.043). Costs were higher with depression and highest with psychotic disorders ($39,564 vs. $40,787 vs. $42,362; P < 0.001). LOS was higher with depression and highest with psychotic disorders (4.10 vs. 4.36 vs. 4.81 days; P < 0.001).
CONCLUSIONS: Depression and psychotic disorders are common in PCDF and are linked to worse outcomes and higher resource use.