Marco Tescione, Annalisa Piccolo, Eugenio Giuseppe Vadalà, Claudio Franzutti, Domenica Donato, Simone Pantano, Manuela Macheda, Eustachio Agricola, Matteo Cameli, Maurizio Cusmà-Piccione, Antonio De Luca, Roberta Manganaro, Giovanna Di Giannuario, Sebastiano Macheda, Concetta Zito, This Document was Promoted by Members of the 2024–2026 SIECVI Scientific Documents Committee and Reviewed by, Giovanni Di Salvo, Scipione Carerj, Giorgio Faganello
Sepsis and septic shock remain major causes of morbidity and mortality and are frequently complicated by multiple organ dysfunction, making management particularly challenging for intensivists. Early recognition of hemodynamic instability, prompt identification of the infectious source, and timely interventions are crucial to improve outcomes. Bedside point-of-care ultrasound (POCUS) is a safe, rapid, and noninvasive tool that supports real-time assessment of the septic patient, guiding both diagnosis and treatment. A structured POCUS approach can be used for initial hemodynamic evaluation, detection of infectious foci, and ultrasound (US)-guided therapeutic procedures directly at the bedside. In addition, the relatively low cost and portability of US make it especially valuable in low-resource settings, promoting more standardized and equitable care. This article provides a practical guide to the use of bedside US in patients with sepsis and septic shock admitted to the intensive care unit, focusing on key views, essential findings, and their implications for clinical management.