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◆ Journal of cardiovascular echography2026-01-01

Cocaine Induced Cardiomyopathy Presenting with Cardiac Arrest: Insights from Cardiac Magnetic Resonance.

Francesco Mori, Mattia Alberti, Simona Chiusolo, Gabriele Masini, Valentina Barletta, Emanuele Neri, Lorenzo Faggioni, Doralisa Morrone, Raffaele De Caterina, Giovanni Donato Aquaro

原始摘要(英文原文)· Original abstract
Cocaine abuse is associated with a broad spectrum of cardiovascular complications, including myocardial ischemia, arrhythmias, and cardiomyopathy. However, chronic myocardial injury may remain subclinical, delaying diagnosis until an acute event occurs. We present the case of a 49-year-old man with a history of chronic cocaine use who was admitted following an out-of-hospital cardiac arrest. A post-Return of Spontaneous Circulation Point-of-Care Ultrasound revealed mildly reduced left ventricular systolic function, while coronary angiography excluded obstructive coronary artery disease. Cardiac magnetic resonance (CMR) imaging demonstrated mid-wall late gadolinium enhancement and patchy T1 elevation, consistent with nonischemic myocardial fibrosis and edema. A subcutaneous implantable cardioverter-defibrillator was placed for secondary prevention, and beta-blocker therapy was initiated. Genetic testing for inherited arrhythmogenic and cardiomyopathic conditions was also undertaken. This case underscores the potential for clinically silent cocaine-induced cardiomyopathy and highlights the value of CMR in detecting subclinical myocardial injury.
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Cocaine Induced Cardiomyopathy Presenting with Cardiac Arrest: Insights from Cardiac Magnetic Resonance. — 科研速览 Science Skim