Yuanyuan Liu, Xiao Dong, Xi Chen, Simiao Zhang, Xuehong Chu, Wanwan Zhang, Erlan Yu, Xiaole Jia, Chuanjie Wu, Xunming Ji
Idiopathic intracranial hypertension (IIH) is a disease that predominantly affects obese women of reproductive age. As obesity rates increase globally, the incidence of this disease is also on the rise. Elevated intracranial pressure without secondary etiology is the main diagnostic feature of this disorder; however, little is known about its underlying pathophysiologic mechanisms. Headache, blurred vision, and pulsatile tinnitus are its main clinical features. With increasing evidence that IIH is a systemic metabolic disorder, many studies targeting the metabolism of patients with IIH continue to emerge, aiming to provide more therapeutic options for patients with IIH. In this review, we highlight recent advances regarding the pathogenesis and treatment of IIH in adults. Finally, we briefly discuss future research directions.