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◆ Folia medica2026-06-25

Recurrent total knee arthroplasty aseptic loosening in a patient with hypophosphatasia: are they related? A case report.

Giulia Lazzeri, Damiano Antognetti, Nicola Piolanti, Vittoria Bettarini, Paolo Domenico Parchi, Vanna Bottai

原始摘要(英文原文)· Original abstract
Hypophosphatasia (HPP) is a rare metabolic bone disease caused by deficient alkaline phosphatase activity, leading to impaired mineralization. While total knee arthroplasty (TKA) is a common treatment for end-stage knee arthritis, its outcomes in patients with metabolic bone disorders like HPP are poorly documented.
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Recurrent total knee arthroplasty aseptic loosening in a patient with hypophosphatasia: are they related? A case report. — 科研速览 Science Skim