Systemic Corticosteroids in the Perioperative Setting for Prevention of Pyoderma Gangrenosum During Reconstructive Surgery.

Pyoderma gangrenosum (PG) is classified as a neutrophilic dermatosis, often presenting as a rapidly enlarging ulcer and associated with inflammatory bowel disease, specifically ulcerative colitis and Crohn's disease. PG has been typically reported to occur after trauma and surgical procedures. We present a unique case of PG following multiple breast augmentation procedures and illustrate various therapeutic strategies to prevent recurrence during subsequent breast reconstruction. The combination of cyclosporine and prednisone was successfully used to prevent PG in this patient when given before and after her third breast surgery. &nbsp.