Olesya M Horlenko, Оksana М Berezovska, Valeriya V Brych, Іryna Yu Pikina, Оlga V Zolina, Volodymyr D Symulyk, Ivan I Pushkash
Conclusions: Recurrent respiratory tract infection is a multifactorial disease caused by a complex interaction of environmental and host factors. We suggest that an "additive effect," depending on the number of factors involved, most of which may be underestimated, may be a plausible explanation for the recurrence of respiratory tract infection in a significant proportion of healthy children with unexplained frequent respiratory symptoms.
OBJECTIVE: Aim: To investigate the influence of risk factors on the development of recurrent respiratory diseases, to analyze clinical and epidemiological components for the possibility of their prevention.
PATIENTS AND METHODS: Materials and Methods: The research was conducted on the basis of the Uzhhorod Children Primary School. Children studied groups (n=118) aged 6-9 years with a diagnosis of "acute recurrent respiratory diseases" were formed.
RESULTS: Results: Childrens inflammatory episodes were most often observed, in particular: bacterial tonsillitis - 86 (72,89%), otitis - 56 (47,46%), pneumonia and sinusitis - 37 (31,36%) (identical indicators). In our study, respiratory infection caused by at least one pathogen was observed in 63,4±4,1% of patients. The proportion of viral infections was 48,34±3,6%, in particular, coinfections were identified in 36,4±2,9% of cases. The distribution of confirmed viruses is as follows: AdV (26,34±1,7%), SARS-CoV-2 (19,5±1,6%), RV (18,2%), RSV (17,8%), influenza A/B (11,4%) and others in minimal structural components (6.8%).
CONCLUSION: Conclusions: Recurrent respiratory tract infection is a multifactorial disease caused by a complex interaction of environmental and host factors. We suggest that an "additive effect," depending on the number of factors involved, most of which may be underestimated, may be a plausible explanation for the recurrence of respiratory tract infection in a significant proportion of healthy children with unexplained frequent respiratory symptoms.