Biochemical pathways for device nanoarchitectonics: organic semiconductors interfaced with biomolecular systems

Abstract This review discusses organic semiconductors interfaced with biomolecular systems, focusing on the construction of material systems through biochemical pathways for device nanoarchitectonics. The initial section highlights biosensors as representative applications at the interface of device engineering and biosystem science. The subsequent sections describe nanoarchitectonics approaches for the synthesis and organization of organic semiconductor devices using bioprocessing. In particular, doping of organic semiconductors in water under ambient conditions coupled with bioprocessing are emphasized, including proton-coupled electron transfer and sugar redox reactions. Inspired by the sophisticated molecular architectures that enables ultra-high-level functions in biological systems, nanoarchitectonics is expected to facilitate further advances in organic semiconductor biodevices.