Potencial antimicrobiano de extractos de espirulina [Arthrospira maxima] obtenidos por extracción con CO2 supercrítico

This study evaluated the antimicrobial potential of Arthrospira maxima extracts obtained using supercritical CO2 under different temperatures [35-40 °C] and pressure [150-200 bar] conditions. The evaluated conditions influenced the extraction kinetics, cellular disruption, and selectivity of the extracted compounds. UV-Vis analysis revealed a higher extraction of compounds in the 400-500 nm region. The highest antimicrobial activity was observed at 10 µg/µL against Escherichia coli. The treatment at 40 °C-150 bar showed the best performance, with a yield of 17.80 ± 2.15 mg/g of sample, a higher extraction rate [k = 0.07 min⁻¹], a greater content of compounds absorbing in the near-UV region [λmax = 447 nm], and a relative inhibitory activity against Escherichia coli of 87.7%. These findings highlight the potential of supercritical CO2 for obtaining antimicrobial extracts from A. maxima.